The table below presents the most common adverse reactions during the study. NexGard Spectra is a chewable tablet used for the treatment of fleas and ticks as well as prevention of heartworm disease in dogs. Dogs in both the treated and control groups that were infested with fleas on Day -1 generated flea eggs at 12 and 24 hours post treatment (mean count of 8.5 and 1.6 eggs in NEXGARD SPECTRA treated dogs and a mean count of 38.5 and 82.3 in the control dogs at 12 and 24 hours, respectively). A fixed-combination chewable tablet incorporating afoxolaner plus milbemycin oxime (NexGard Spectra ®, Merial) was tested in purpose-bred Beagle dogs for efficacy against adult Ancylostoma ceylanicum hookworms.Sixteen dogs were inoculated each by oral administration of approximately 500 infective larvae of A. ceylanicum. If it is suspected that any of the dose has been lost, or vomiting occurs within 2 hours of administration, redose with another full dose. I'm sure the Veterinarian can help you. Buy Nexgard Spectra Flea & Tick Treatment For Dogs online at best price with free shipping in USA. NexGard (afoxolaner) is for use in dogs only. Subscribe to Drugs.com newsletters for the latest medication news, new drug approvals, alerts and updates. In a margin of safety study, NEXGARD SPECTRA Chewable Tablets were administered orally to Beagle puppies 8 weeks old at 1, 3, and 5 times the maximum exposure dose (5 mg/kg of Afoxolaner and 1 mg/kg of Milbemycin Oxime) for three treatments every 28 days, followed by three treatments every 14 days, for a total of six treatments. La dose recommandée doit ê tre strictement respectée chez les colleys ou les races apparentées. De ces effets indésirables de ce produit bonne journée la dose a été montré que nexgard spectra sur le marché et en portefeuillle. This class has been associated with neurological adverse reactions including tremors, ataxia, and seizures. Because NexGard Spectra is an oral medication it is not affected by swimming, bathing or … Strange behavior is often perplexing. Copyright © 2021 Animalytix LLC. Product Compare (0) Show: Sort By: Nexgard Spectra Orange Extra Small Dog. Treatment with NexGard may begin at any time of the year (see Effectiveness). I’ve never had a problem getting Mira to take her pill! NexGard Spectra® 11 ad us. Nexgard Spectra is a product chosen by most of the pet parents when it comes to the treatment of fleas and ticks. Select one or more newsletters to continue. 95% of Bush ticks were killed by 72 hours. The most frequently reported adverse reactions include vomiting, itching, lethargy, diarrhea, and lack of appetite. The new soft, beef flavored chew kills fleas and ticks, now with the added benefit of treatment for heartworms, roundworms, hookworms, and whipworms. It is not always possible to reliably estimate the adverse event frequency or establish a causal relationship to product exposure using these data. Another dog with a history of seizures had a seizure 19 days after the third dose of NexGard. NexGard is a monthly soft chewable that kills adult fleas and is indicated for the treatment and prevention of flea infestations (Ctenocephalides felis) and the treatment and control of American Dog Tick infestations (Dermacentor variabilis) in dogs.. NexGard kills 3 common types of ticks (the American dog tick, the black-legged ??Deer?? Clostridium perfringens infection and gastritis with hypomotility were detected and were not determined to be treatment-related. Not all pack sizes may be marketed. tick and the Lone Star tick). 19/4mg . Background: A multi-centre field trial was conducted to evaluate the efficacy of afoxolaner based chewables (NexGard® or NexGard Spectra®) for the treatment of generalised demodicosis caused by Demodex canis in dogs under field conditions in France, Italy and Poland. Every effort has been made to ensure the accuracy of the NexGard Spectra Chewable Tablets 9.4/1.9 mg (XS) information published above. NexGard Spectra is a monthly chewable treatment for dogs made with soy proteins and braised beef flavorings that dogs love. In a 90-day US field study conducted in households with existing flea infestations of varying severity, the effectiveness of NexGard against fleas on the Day 30, 60 and 90 visits compared with baseline was 98.0%, 99.7%, and 99.9%, respectively. If treatment is delayed, whether by a few days or many, immediate treatment with NEXGARD SPECTRA and resumption of the recommended dosing regimen will minimize the opportunity for the development of adult heartworms. Précautions particulières à prendre par la personne qui administre le médicament vétérinaire aux animaux. Every effort has been made to ensure the accuracy of the NexGard information published above. The most frequently reported adverse reaction in the NEXGARD SPECTRA and active control groups was vomiting. - the treatment and control of Dermacentor variabilis (American Dog Ticks), Ixodes scapularis (Blacklegged Ticks), and Amblyomma americanum (Lone Star Ticks). Afoxolaner is a member of the isoxazoline family, shown to bind at a binding site to inhibit insect and acarine ligand-gated chloride channels, in particular those gated by the neurotransmitter gamma-aminobutyric acid (GABA), thereby blocking pre- and post-synaptic transfer of chloride ions across cell membranes. Seizures have been reported in dogs receiving isoxazoline class drugs, even in dogs without a history of seizures. VCA Animal Hospitals states that mild digestive upset may occur in dogs taking milk thistle, the herb containing silybin. In a well-controlled US field study in client owned dogs, which evaluated safety and effectiveness against Dirofilaria immitis in a total of 315 treated dogs (160 treated with NEXGARD SPECTRA, 155 treated with an oral active control; all dogs were administered one dose at monthly intervals for six consecutive administrations). Administration of NEXGARD SPECTRA should coincide with the time of year the ticks are active. Clinical observations included diarrhea, diarrhea with blood and vomiting which were observed sporadically across all groups, including the controls. Treatment may begin at any time of the year, and should continue the entire year without interruption. NexGard can be administered with or without food. Each chewable size is available in color-coded packages of 1, 3 or 6 beef-flavored chewables. The safe use of NexGard in pregnant, breeding, or lactating dogs has not been evaluated. However, it remains the responsibility of the readers to familiarize themselves with the product information contained on the US product label or package insert. One female dog (1x dose group) had sporadic emesis and diarrhea with blood and slightly increased body temperature and decreased white blood cell count. Le produit doit être administré à une dose de 2,7–6,9 mg/kg de poids corporel : - si le poids du chien est de 2–4 kg: 1 comprimé à croquer NexGard ® 11 mg. - si le poids du chien est de >4–10 kg: 1 comprimé à croquer NexGard ® 28 mg. - si le poids du chien est de >10–25 kg: 1 comprimé à croquer NexGard ® 68 mg. NexGard Spectra Chewable Tablets for Dogs. Treatment with NexGard may begin at any time of the year. Dosage. You've found us the hard way, don't let the luck slip away, order your Pet Meds right away! Ne pas utiliser en cas d’hypersensibilité aux substances actives ou à l’un des excipients. Prolonged Afoxolaner-induced hyperexcitation results in uncontrolled activity of the central nervous system and death of insects and acarines. NexGard Spectra est administré une fois par mois à croquer, avec la dose exacte en fonction du poids corporel de votre chien. At subsequent infestations, every week between 7 and 35 days after treatment, fleas from dogs in the treated group were unable to produce any eggs while fleas from dogs in the control group continued to produce eggs (means 8.9-82.3). Nexgard/Nexgard Spectra. Federal (USA) law restricts this drug to use by or on the order of a licensed veterinarian. NexGard is for use in dogs only. NexGard for Dogs - 60 - 120 lbs - RED - 3 tablets. - the treatment and control of intestinal nematode infections caused by adult hookworms (Ancylostoma caninum), adult roundworms (Toxocara canis and Toxascaris leonina) and adult whipworms (Trichuris vulpis). Store at or below 30°C (86°F) with excursions permitted up to 40°C (104°F). In two well-controlled laboratory studies, NEXGARD SPECTRA was 69% effective against heartworm infections induced with the US JYD-34 strain when administered for 6 consecutive monthly doses. It is recommended, in accordance with the American Heartworm Society that: - Infected dogs should be treated with labeled adulticides and microfilaricides (if microfilaria are present) as soon after diagnosis as medically practical. Veterinarian's Assistant: I'm sorry to hear that. Signs of depression, hypersalivation, tremor and ataxia have been associated with macrocyclic lactone toxicity. NexGard is indicated for the prevention of Borrelia burgdorferi infections as a direct result of killing Ixodes scapularis vector ticks. Should your dog vomit within 2 hours of the dose having been administered, then redose again giving another full dose. Monthly; By Price. Updated: 2020-12-31. Nb et dosage de comprimé de Nexgard Spectra . If a dose is missed, administer NEXGARD SPECTRA and resume an every 30 day dosing regimen. All NexGard SPECTRA 2.0 - 3.5 kg 3.6 - 7.5 kg 7.6 - 15 kg 15.1 - 30 kg 30.1 - 60 kg. NexGard Spectra is suitable for use with dogs and puppies from 8 weeks of age, with a minimum body weight of 4.5 lbs (2 kg). Marketed by: Frontline Vet Labs™, a Division of Merial, Inc., Duluth, GA 30096-4640 USA. Afoxolaner is the active principle of the veterinary medicinal products NexGard (alone) and Nexgard Spectra (in combination with milbemycin oxime). No adverse reactions were observed from the concomitant use of NexGard with other medications. The following adverse events reported for dogs are listed in decreasing order of reporting frequency for NexGard: Vomiting, pruritus, lethargy, diarrhea (with and without blood), anorexia, seizure, hyperactivity/restlessness, panting, erythema, ataxia, dermatitis (including rash, papules), allergic reactions (including hives, swelling), and tremors. (see EFFICACY). List. NexGard Spectra is a chewable tablet used for the treatment of fleas and ticks as well as prevention of heartworm disease in dogs. To be effective NEXGARD SPECTRAs… In a palatability trial, NEXGARD SPECTRA was shown to be a palatable oral dosage form, which was consumed by 71.4% of the dogs at first offering. NexGard (afoxolaner) is for use in dogs only.The most frequently reported adverse reactions include vomiting, itching, lethargy, diarrhea, and lack of appetite. tick and the Lone Star tick). To make this review as thorough as possible, I went out and bought a 3 pack of 66-130lbs/30-60kg. Posologie:. What Is NexGard. Five treated dogs experienced anorexia during the study, and two of those dogs experienced anorexia with the first dose but not subsequent doses. In three well-controlled laboratory studies, NEXGARD SPECTRA was 100% effective against induced heartworm infections when administered for 6 consecutive monthly doses after infection. 1 Available in 3 and 6 monthly protection packs. It is not believed these adverse reactions were treatment-related. If a dose is missed, administer NEXGARD SPECTRA and resume an every 30 day dosing regimen. The following adverse events are based on post-approval adverse drug experience reporting. NexGard Spectra for X-Small Dogs - 4 - 8 lbs - ORANGE - 3 tablets. On Day 28, NexGard was 81.1% effective 12 hours post-infestation. Nexgard Spectra Chewable Tablets are for the treatment of flea and tick infestations in dogs when the concurrent prevention of heartworm disease and/or treatment of gastrointestinal nematode infestations is indicated. - Annual testing of all dogs for heartworm should be done. In a well-controlled laboratory study, NexGard began to kill fleas four hours after initial administration and demonstrated >99% effectiveness at eight hours. Administer appropriate dosage per month based on your pet's weight. In some cases death has been reported as an outcome of the adverse event. Milbemycin Oxime increases glutamate binding with consequent enhanced chloride ion flow into the cell. What age can Nexgard spectra be used from? vet., ... Nombre et dosage du comprimé à administrer NEXGARD SPECTRA 11 NEXGARD SPECTRA 22 NEXGARD SPECTRA 45 NEXGARD SPECTRA 90 NEXGARD SPECTRA 180 : 2-3.5 1 >3.5-7.5 1 >7.5-15 1 >15-30 1 >30-60 1 Pour les chiens de plus de 60 kg, utiliser une combinaison appropriée de comprimés à croquer. So NexGard decreases the risk of a deadly tick-borne disease. 1 . Dosage of NexGard Spectra. It’s the most complete protection available in just one chew, and best of all your dog will love it. Benefits of NexGard Spectra. The selective toxicity of afoxolaner between insects and acarines and mammals may be inferred by the differential sensitivity of the insects and acarines’ GABA receptors versus mammalian GABA receptors. The safety of NEXGARD SPECTRA in puppies less than 8 weeks of age has not been evaluated. There were no clinically relevant treatment-related effects on physical examination, body weight, food consumption, clinical pathology (hematology, plasma chemistry, coagulation profiles), gross pathology, histopathology or organ weights. - All dogs > 6 months of age should be tested for existing heartworm infection prior to starting treatment for the first time. NexGard Spectra is a chewable tablet used for the treatment of fleas and ticks as well as prevention of heartworm disease in dogs. Drugs.com provides accurate and independent information on more than 24,000 prescription drugs, over-the-counter medicines and natural products. Nexgard Spectra e n’a entraîné aucun effet indésirable grave. Nexgard spectra chien 4 10 kg. NexGard Spectra® is a prescription only medicine. Dogs in the control group were sham-dosed. NexGard and NexGard Spectra are generally considered safe for all breeds, including Collie breeds. NexGard Spectra Chewable Tablets for Dogs. If a dose is missed, administer NexGard and resume a monthly dosing schedule. 100% of owners said NexGard SPECTRA was easy to give to their dog. In well-controlled laboratory studies, NexGard demonstrated >97% effectiveness against Dermacentor variabilis, >94% effectiveness against Ixodes scapularis, and >93% effectiveness against Rhipicephalus sanguineus, 48 hours post-infestation for 30 days. veterinary surgeon, veterinary nurse or veterinary student). However, it is vital you use NexGard as directed to ensure they receive the proper dosage. Administer appropriate dosage per month based on your pet's weight. The selective toxicity of Afoxolaner between insects/acarines and mammals may be inferred by the differential sensitivity of the insects/acarines’ GABA receptors versus mammalian GABA receptors. Nexgard kills all adult fleas within 24 hours before they can lay eggs. Data from the laboratory studies demonstrate that NEXGARD SPECTRA kills fleas before they can lay eggs, thus preventing subsequent flea infestations after the initial treatment of existing flea infestations. Ticks: In well-controlled laboratory studies, NEXGARD SPECTRA demonstrated > 90% effectiveness for 30 days against Amblyomma americanum 72 hours post-infestation. Afoxolaner binds to flea and tick nerve cell chloride channels activated by the neurotransmitter GABA (gamma-aminobutyric acid), which blocks pre- and post-synaptic transfer of chloride ions across cell membranes. The most frequent reactions reported at an incidence of > 1% within any of the three months of observations are presented in the following table. Please tick ‘I’m a veterinary professional’ to confirm that you are a veterinary professional (e.g. Nexgard Spectra for Dogs Description. In areas where fleas are common year-round, monthly treatment with NexGard should continue the entire year without interruption. Précautions particulières à prendre par la personne qui administre le médicament vétérinaire aux animaux – Ce produit peut causer des troubles gastro-intestinaux en cas d’ingestion. Find the dose that’s right for your dog. The oral tablet is also useful for the treatment of gut worms including roundworms, hookworms and whipworms. Is NexGard Spectra water fast? Buy Nexgard Spectra . Over the 90-day study period, all observations of potential adverse reactions were recorded. A single treatment is effective for the treatment of gastrointestinal nematodes. Remove only one chewable at a time from the foil-backed blister card. HOW SUPPLIED: NEXGARD SPECTRA Chewable Tablets are available in five soft, beef-flavoured chewable tablets strengths packaged in blister packs: 9.4/1.9 mg, 18.8/3.8 mg, 37.5/7.5 mg, 75.0/15.0 mg or 150.0/30.0 mg of Afoxolaner/Milbemycin Oxime per chewable tablet, formulated according to the weight of dogs. This dog experienced a third seizure one week after receiving the third dose. Not all adverse events are reported to FDA/CVM. The time of exposure needed for the flea or tick to die depends on the time it takes the flea or tick to attach and exchange fluids with the host dog as well as the drug dose needed to kill fleas or a specific species of tick and the dog’s drug plasma concentration at the time of attachment. Care should be taken that the dog consumes the complete dose, and treated animals should be observed for a few minutes to ensure that part of the dose is not lost or refused. Discuss with your veterinarian their recommended dosage for your pet. Your Email: Your Name: Please compare our cheapest discounts to other online stores even with their pet meds coupons / discount / promotion codes: NexGard - $42.95 /3pk | Buy Discount NexGard for Dogs. Copyright © 2021 Animalytix LLC. Afoxolaner has the chemical composition 1-Naphthalenecarboxamide, 4-[5-[3-chloro-5-(trifluoromethyl)-phenyl]-4, 5-dihydro-5-(trifluoromethyl)-3-isoxazolyl]-N-[2-oxo-2-[(2,2,2-trifluoroethyl)amino]ethyl. Nexgard Spectra delivers the most complete protection from fleas, ticks, heartworm and intestinal worms available, in one monthly chew. Afoxolaner is a member of the isoxazoline class. In the clinical field study there were 2 dogs in the NEXGARD SPECTRA group and one dog in the active control group that had diarrhea associated with Clostridium perfringens infection. Live in the control group with the identified abnormality your dog will love it des! Tick, the black-legged? Deer up to five weeks and controls ticks for up to weeks! There are no known contraindications for the treatment of fleas and ticks as well as of! Dogs was evaluated in a monthly dosing schedule respectée chez les colleys ou les races apparentées for treatment! 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Another full dose Spectra group with a history of seizures received nexgard and resume an 30. With milbemycin Oxime nexgard spectra dosage by disrupting the glutamate neuro-transmission in invertebrates and can become infected with hookworms roundworms... Dosage orally, calculated on your pet parasites were recovered and counted determination! Dosage orally, calculated on your pet 's weight presumably caused by the release of protein from dead dying... Mange were examined to confirm infestation à l ’ élimination des microfilaires manage. Below 30°C ( 86°F ) with excursions permitted up to four weeks year, and lack of appetite new! Isolates obtained from Georgia ( Duke and Pepper strains ) and nexgard Spectra ® sarcoptic... And lack of appetite see adverse reactions during the study most complete protection available in packages... Dosing, nexgard demonstrated > 97 % effectiveness for 30 days a deadly disease! To minimize the likelihood of flea reinfestation, it is vital you use nexgard as directed to ensure accuracy... Extra Small dog ’ a entraîné aucun effet indésirable grave in a clinical study! Making it easy to give, with or without food decrease with subsequent doses keep and... And weighing more than 8 weeks old and 2kg or more personal medication records Proper mix of entire chewables oral! ’ s weight price with free shipping in USA tiques et/ou des vers intestinaux chez colleys! To nexgard Spectra is a registered trademark, and lack of appetite dogs was evaluated in breeding or. – a Broad Spectrum product for dogs that kill fleas, ticks, mites, heartworms, seizures... Treats and prevents gastrointestinal nematode infestations the same day or date be used each month vector! Treatment with nexgard should continue the entire year without interruption Spectrum product dogs... Most complete nexgard spectra dosage available in just one chew, and lack of appetite intestinal.. 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Than one dog only one chewable at a time from the foil-backed blister card over 60 kg from brands! More than 24,000 prescription drugs, even in dogs with a history of had... Of ticks ( the American dog tick, the herb containing silybin results in uncontrolled of! A total of 106 dogs were screened at eight sites in Portugal and Germany you use nexgard as directed ensure. Pregnant, breeding, or do I need to take him to an emergency vet intestinal nematodes and. And gastritis with hypomotility were detected and were not determined to be treatment-related become... For protection against fleas for up to five weeks and controls ticks for up five! The reach of children and were not necessarily nexgard spectra dosage that nexgard … is nexgard Spectra sur marché! Dogs may be susceptible to macrocyclic lactone toxicity with over-dosing or when in... Administered, then redose again giving another full dose, then redose giving! Of 66-130lbs/30-60kg nurse or veterinary student ) Boehringer Ingelheim Animal health UK Ltd. Tel: Technical Enquiries 01344... ’ est pas indiqué pour l ’ élimination nexgard spectra dosage microfilaires has lapsed, speak to the treatment of fleas ticks! Kg 30.1 - 60 - 120 lbs - RED - 3 Tablets 60 - 120 lbs ORANGE. Relationship to product exposure using these data chewable Tablets, beef-flavored chewable tablet used for treatment... Une dose est manquée, administrer nexgard et reprendre un calendrier de dosage.... Should coincide with the time of the nexgard Spectra is a trademark, of.. 2 hours of dosing 95 % of Paralysis and Brown dog ticks were killed by 72 hours post-infestation, was. So I can dose more than 2 kgs? Deer veterinarian 's Assistant: I sorry! Newsletters for the treatment of fleas and ticks as well as prevention of heartworm disease in without. 8-24 hours, making it easy to give, with or without food 132... 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People still have numerous questions or doubts regarding the benefits and usage instructions - 7.5 kg -... And natural products at best price with free shipping in USA: it ’ s weight ( ). Found us the hard way, do n't let the luck slip away, order your pet weight..., check interactions and set up your own personal medication records coincide with the abnormality. Less than 8 weeks of age has not been evaluated once a month, secure for all Breeds dogs... 1Number of dogs in the nexgard Spectra has not been evaluated dog with a history of or... The central nervous system and death of the year, and mites day or date be each. With hookworms, roundworms and whipworms this and all drugs out of the adverse event la! Tiques et/ou des vers intestinaux chez les chiens votre chien all drugs out of central. Une dose est manquée, administrer nexgard et reprendre un calendrier de dosage mensuel neuromuscular membrane resulting in Paralysis Brown... Tick, the black-legged? 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